Millions of people all over the world may be able to get a convenience from New medicine Which uses antibiotics instead of pain relievers to treat the condition.
Doctors who tested the medicine said that it might be “gamechanger” for a person of every four people causing back pain under the infection rather than a muscle or spine problem.
An early stage of the drug found that six out of 10 of those who took great benefits, including a significant decrease in the pain and disability they had previously suffered.
The drug, called PP353, is under development by Persica Pharmaceuticals, a company in the field of biotechnology in Kent. The trial organized in conjunction with six NHS hospitals in England and Wales.
Dr. Shiva Trebathi, a NHS pain consultant and chief researcher in the trial, said if the drug is approved by the organizers and becomes available, it will be “Gamechanger for Chronic Lower Back Pain at similar levels such as [how] Antibiotics caused a difference in infection. Because if we are able to get this 25 % of patients with chronic low back pain to work, then there is no return to any medications, it is not due to any disability, then I think [that] It will be the huge gamechanger for the future. “
However, the random experience that controls only 44 patients – 22 in Britain and 22 in Spain, Denmark and New Zealand – so the PP353 will have to undergo more experiments, and are supported by drug control, before doctors can provide patients to relieve their symptoms.
All patients had severe back pain for at least six months, and in some cases more than five years, she did not respond to traditional treatment, such as pain -related drugs.
Persika said that a great advantage of treating it is that the patient has an injection for four days separately instead of undergoing surgery or tablets for a long time. recently I found research Most of the 56 methods of trying to relieve the back pain studied by the researchers – starting with massage and acupuncture to pain relievers and physical therapy – have said little or non -existent.
PP353 is a mixture of three substances already used widely in medicine: Linzolid, antibiotic; IOHEXOL, contrast or dye worker; And gel sensitive to heat. It is injected in the lower back to remove the infection that has evolved around the tablets.
“The first experience of our patient has truly positive results,” said Steve Roston, CEO of the company. [It produced] Great discounts in pain and disability and [patients also got] Clinical significance and statistically significant benefit. The possibility of the patient’s use is enormous.
If you can reduce the pain and disability that people live together [trial] Patients have responded, and will change their lives. “
He added that market research shows that 2 million people in the United States and 250,000-300,000 in the United Kingdom can benefit. “Millions of people around the world can take advantage of this. But low back pain is not just a problem in the first world; everyone gets low back pain.”
Roston added that the drug is different from other back pain, as it targets the main cause of the problem rather than just its main symptoms – pain.
Lower back pain It is one of the most health problems in the world. Six out of 10 people in the UK develop it at some point. It is expected to grow as a lady around the world due to the growing and growing population aging. It is often difficult to diagnose and even successfully treat it.
Persika said that many patients in the experiment had suffered a decrease in the amount of pain they were suffering from within a month of injection and still feel a great improvement after a year. However, it decreased, but it did not remove, the need to continue to eat pain relievers, added Ruston.
But Dr. Benjamin Ellis, a consultant of a rheumatic specialist at the Impierial Healthcare NHS TRUST in London, a chronic pain specialist, expressed his doubts about PP353 capabilities.
“Modern medicine has greatly failed people with chronic pain-other words, in the long run-back pain. But there is little evidence that interventions that use surgery or injections, or even taking medications, make a big difference for the vast majority of people with chronic lower back pain.
“People with low back pain are desperate, desperate, understandable for anything that can help. There is also a huge industry in providing techniques and medications that claim to help, but there is little evidence that this does.
“Promising comprehensive curricula, such as cognitive functional therapy, do not look at it, especially when the services are exaggerated.
“However, if there is a sub -group of people with low back pain that can benefit reliably and safely from a simple pair of injection, then this will be great news – but it seems unlikely.”
