Why are our angers swelling when you walk or turn our skin to red – or inflamed – when it is scraped?
This fast response is caused by inflammation – and can save your life.
Dr. Robert Schmillang, a rheumatic specialist and faculty member at the Harvard University Faculty of Medicine, said, who helped the author of a Report on inflammation.
Inflammation is exposed to its fire due to its association with a variety of chronic diseases, including diabetes, heart disease and even allergies. Even longers seek to reduce chronic inflammation as a healthy aging key.
“It is a two -edged sword.”
Inflammation is necessary to survive, and without that our bodies will not be able to fight infiltrators such as viruses and bacteria. Dr. Moshe Ardi, a pediatrician and director of the Center for Infectious and Immunology Research at the Cedar-Skyce Center in Los Angeles, said sore throat, for example, turns red and is painful because the immune system fights infection to prevent it from spreading, which doctors call acute inflammation.
He said: “The local immune response in the acute stage – to a limited extent – are all beneficial.”
The discovery of inflammation is due to the centuries to the Romanian encyclopedia Aulus Cornelius Celcus, one of the first people to determine it. Celcus described the basic signs of inflammation in Latin Roborand tumorand Calorand Delor. Terms are translated into redness, swelling, heat and pain, which are still possible.
At the microscopic level, acute inflammation includes liquid transmission of our bodies, proteins and white blood cells to the sites of infections or injuries, which help fight foreign pathogens and enhance recovery.
Although inflammation can be a short -term savior, there is another type of inflammation and chronic inflammation, which can harm the body in the long run.
What causes chronic inflammation?
Many risk factors make your body more vulnerable to chronic inflammation-including obesity, which enhances low-level infections throughout the body, smoking tobacco and diet.
Dr. Thadius Stapnobic, chief of inflammation and immunity at the Cleveland Clinic, is suspected that the modern American diet is a major source of chronic inflammation.
Manufactured foods, refined sugars, unsaturated fats and excessive consumption of red meat are associated with increased inflammation. The Food and Drug Administration has been banned R.Fat ransom In 2015, it was recently removed from snacks, bread, cookies and other baked goods in 2018.
“I think there are more people with chronic inflammation than in the past,” said Stappeenbeck. ))
“The lack of exercise, a lack of sleep, and a lot of tension, all of these are related lifestyles that are supportive of infections,” Shamling said.
What are the symptoms of inflammation?
The signs may differ, but they include:
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Unforgettable joint pain.
Shamilling said that weight loss, exercise and avoiding very processed foods can reduce the levels of inflammation in the body. Studies have suggested that After following a Mediterranean dietLargely based on the plant with a focus on whole fruits and vegetables, can Reducing inflammatory levels.
“It is often not a kind of switch,” he said. “We do not have perfect ways to measure inflammation after lifestyle modification, but inflammatory signs can improve with lifestyle changes.”
How chronic inflammation affects the heart
Estimate 129 million people in the United States They have at least one chronic disease, according to the Centers for Disease Control and Prevention. The spread of chronic disease It grew about 7 million people every five yearsAccording to estimates from Stanford University.
The causes of chronic disease are complex, but experts are increasingly convinced that inflammation plays a role.
“There is a good amount of consensus that many of the chronic diseases that we see now are in the spread of what they were in the past can be associated with chronic inflammation,” said Shmerling.
What comes first – inflammation or disease? When the body is in an inflammatory state, it can begin to destroy the same things that it needs to work, such as our vital organs and blood vessels.
“Continuing inflammation may lead to heart disease and plaque building in the blood vessels, which may lead to a heart attack and strokes.
Ethical immunity disorders such as lupus or multiple sclerosis are also associated with chronic inflammation, as the immune system begins to attack different parts of the body in friendly fire.
“The body is not properly distinguished between it and an external infiltrator or pathogens,” said Schmelling. “There is a very continuous and destructive chronic inflammation.”
Stepnbick said that diseases, including Parkinson’s and even diabetes, have inflammatory ingredients. Because of the relationship of close inflammation with a group of diseases, he was not surprised by the coming patients who ask to verify this.
He said: “I think there is a desire from patients to say, can you discover this in me earlier, before I feel the superior disease?”
Is there a test for chronic inflammation?
There are blood tests for inflammation, but they are not perfect. They do not provide clear answers to the place where inflammation may be inherent in the body.
There can also be false positives. For this reason, experts say that tests with symptoms should be interpreted.
One of the most common tests is called red blood cell sedimentation, a blood test that measures the level of some proteins that are associated with the amount of inflammation in the body.
Another test evaluating the C-Eactive (CRP), which is a protein that produces the liver in response to inflammation.
Because of the restrictions, the Shmerling does not recommend that healthy people who have no routinely symptoms of inflammation be examined.
He said: “There can be natural inflammatory tests even when the inflammation is present, and sometimes the tests are unnatural even when it does not seem to be any present.” “So it’s not perfect.”
STAPPENICK agreed.
“I don’t think there are a lot of courses for that, in reality,” he said.
There is some potential for a test called HS-CRP, a more sensitive test that can find smaller increases in the interactive protein C in the blood. High levels of this protein in the blood have been linked to heart attacks and strokes.
Some argue that this test should be done routinely, just like cholesterol examination, to determine who is more likely to risk heart attacks and stroke.
However, the evidence was mixed, which is why the test was not widely taken.
“There are so low or highly dangerous people that CRP is unlikely to help you,” said Schmelling. “There are sub -groups of people, perhaps in a moderate danger, as CRP can be useful.”
This article was originally published on NBCNEWS.com
