Now is the time for a COVID-19 synthesis

R.It is the first day Among the first university session on evolutionary medicine comes with the evacuation of a new responsibility, it was presented after we wiped the curriculum and discussed my policies on attendance, residence and other precise printing: we will not spend a great time talking about Covid-19. This is in response to the observation that my interaction with people from many aspects of life: We all suffer from social syndrome called by some “fatig”, in which any mention of the epidemic is mentioned by our human central treatment units, and we immediately lose interest in the conversation. (This social version of Covid is a play on words, where the term can also describe the clinical consequences of the long presence of individuals.)
While I surrendered to fatigue social media at the level of the semester, I now decided-after more than five years of the arrival of the SARS-COV-2 to us-that we need to mobilize energy to think about the epidemic and extract some permanent messages to help us rethink many aspects of science and the world.
My semester announcement seems unnecessary at best, and is likely to be a bad educational strategy, because Covid-19 is one of the greatest examples of development in scientific history. But avoiding this topic is the product of its own selective process, and its history dates back to when I taught microbial development in early 2020, when society freezes. Even though, before closing, I saw glass expressions with glass-a mixture of fear, confusion and exhaustion-from students in every male of the epidemic. Since the fall of 2021, when students mostly returned to personal education, the syndrome has worsened. Students did not want – and they didn’t want to talk about it. Our peers does not rise. Nor our family members, book agents, or magazines editors. Certainly we haven’t forgotten what happened. But we act as we hope we can.
This response is logical. It is difficult to find a person whose life was not affected negatively with the epidemic. Many effects did not include the virus at all, but instead, the effects of the indirect, but toxic epidemic on society. We all witnessed the intersection between American epidemic and policy, as government officials made claims that were in opposition to many public health experts (treatment with disease with Hydroxy Chlorocin and IvermectinFor example). This revealed the lack of confidence in science, which appeared along with The rise of tyranny Politics all over the world.
Insurance served as a social tension test for many institutions. It affected the workforce across the sectors and a structure Prison residentsAnd negatively affect children Educational results. Whatever we feel the necessity or effectiveness of social interventions on a large scale in response to the epidemic, we must all agree that-from the perspective of collective life quality-absorbed.
Students did not want – and they didn’t want to talk about it. Our peers does not rise. Nor our family members, book agents, or magazines editors. Certainly we haven’t forgotten what happened. But we act as we hope we can.
In addition to the damage associated with the epidemic and the response to public health, Covid-19 produced many victories for virus research. Starting in early 2020, scientists all over the world have generated meaningful data Published studies At an amazing pace. Scientists have shared data and formed large cooperation networks across the oceans.
On almost a daily basis, we learned about The shape of the virus’s developmentdetails DiseaseAnd unknown before Human pathological physiology. Twenty years ago, I joined with immunosuppressive friends that their field was defined by the laundry menu of cytokines (proteins that control inflammation and other processes) and other facts by heart. Although this was never true, I could no longer use it as humor. Since 2020, we have learned new things about sterilizing immunity, immune memory and other details about viral infections at an amazing level of details. In just a few years, we discovered a ton. The importance of this cannot be exaggerated.
However, about five years after the emergence of the first cases in the United States, our collective fatigue has left us to struggle to extract significant lessons from the ordeal, which we can apply to other infectious disease scenarios and bigger ideas about science and society.
One of the arena that needs clarity regarding our global image of the rules of infectious diseases. To anyone, we learned about Unlimited effects to Transfer without symptoms In formulating epidemics. When diseases can spread quietly through those who are not apparently affected by symptoms, we can easily abuse epidemics, because the number of individuals who suffer from symptoms is a weak scale for the number of people with people.
The transition science without symptoms is associated with the fine details of the interaction of the host nurse, in particular, to the features that differ from one individual to another. The lack of homogeneity has always been the main focus and great ambiguity in epidemics. Why do different people have different experiences with one disease? The question evokes all the challenges in solving complex features, as many genes and different environments contribute to the apparent pattern (the disease in this case). Could the disease be the product of genetic genetic variation? How can demographic features such as age and sex motivating this homogeneity?
Regarding, the Covid-19 pandemic was a referendum on the Disease Modeling Corporation. The arithmetic epidemics were forever, a The decisive part From the science of outbreaks. It allows us to make expectations, simulate the impact of possible interventions, and to inform decisions in public health directly.
But the epidemic also highlighted the challenges with these methods. Many of this was wrapped in the story behind a form developed by Institute of Health Standards and EvaluationOr ihme. IHME is a great group, well trained and very respectful, public health research is conducted on various issues. Early in 2020, the group created a mathematical model describing the shape of the Covid-19 pandemic, controversial, when it ends. Make the form The bold prediction That there is an opportunity (with uncertainty) that cases will be disrupted to zero proximity in the United States by July 2020. Of course, this prediction was incorrect. However, instead of Lambasting Controversy should be an opportunity to reconsider the basic question about the cause and how we represent diseases. Previous successes and failures can reach the new mathematical methods that tell us something meaningful about the dynamics of the disease.
In addition, we need a family gathering around friendly interventions, because there Questions About the ones we have implemented, making a big difference in health results at all. More importantly, this is related to the effectiveness in the real world of interventions, not whether it is rooted in solid science. (I think so much that She was.) As a researcher of infectious diseases, I struggle to accept the idea that what we did did not have a difference. But my feelings do not matter. And do not do for you. We must continue to examine whether and why the interventions may not be important in some settings, and how we can improve them.
Finally, along with the artistic squares described above, the epidemic also learned that the most detected lessons may not be related to the SARS-COV-2 or any details dealing with the basic science of infectious diseases.
When offering official offers on the epidemic, I often ask, “What is the greatest threat to society: the RNA that was the cause of the disease, or the broken communication that undermined the efforts made to provide the responsible messages to the public in citizenship?” The question is the speech, of course, but it is useful for preparing a speech about what problems are.
As a researcher of infectious diseases, I struggle to accept the idea that what we did did not have a difference. But my feelings do not matter. And do not do for you.
Five years later, skeptics of science is now sitting at the top of the offices. Not only live the wrong information and conspiracy on YouTube channels with marginal letters, but are now presented as legitimate alternatives to the data created by people who devote their lives to study the natural world carefully through the scientific method. We now live in an era that can be safely summarized as the end of science peacetimePerhaps the end of general toxicity of higher education institutions once.
Today we must study the epidemic at least a strict level like the first days. The reasons that make us clear: hadith MPOX outbreakReturn MeaslesAnd the risk of Influenza epidemic Highlighting the reason for the need to collect our knowledge of the epidemic. But I am skeptical that we will do it, and I am somewhat sympathetic to the reason. With general fatigue, money dried up higher The charming magazines reject our papers related to the epidemic. In light of this, it is might time to select any new topic that will come to us. The response is unfortunate, but it is logical given the incentive structure, as it pays the research dollars and the highly influencing manuscripts to professional progress. What’s more, we are all dispersed due to political attacks that threaten the existence of the research institution. The scientific community either does not know what to do or does not believe that doing the right thing deserves all this effort. This is a sad fact.
What I barely provided is a combination, but more as a brief list of some messages that may appear if we stop and think. It is now time for the next generation of avengers who overcome their fatigue-19 and apply their training to a new model of the epidemic-which teaches us how pathogens continue to enhance chaos Hoomo, the sane And the non -human types that we care about. But as important, this synthesis should explore how scientists can move in stormy political waters and improve our position among the audience who seems to have stopped attention, perhaps in a understandable way, about what we do.
This article was originally published on Unreasonable. Read The original article.
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