The complexity of female sex hormones calls for more science, not less

In 1977, the US Food and Drug Administration (FDA) imposed a ban on the women of the reproductive era that was included in early drug experiments – even if they used birth control or distinguished partners. This was a reaction to the damage caused by drugs such as Aleedomide, which can lead to birth defects.
Even before the embargo (which was lifted to non-pregnant women in 1993), women and female animals were regularly excluded from research-their volatile hormone levels that are complicated noise. Female data is often independent of research on male animals.
The cost of this lack of implications is clear: it has given our understanding of health and disease, and we are very unaware of cases that often affect women.
A classic example of this came in 2013, when Zolpidem was approved for more than 20 years after more than 20 years of a dose, as this recommended dose appeared for women with evidence, she was suffering from more drowsiness during the day, which led to more driving accidents.
A progress is made. Increasingly, researchers study sex as an important biological variable, which leads to modern discoveries that women Two times most likely As men who are diagnosed with depression, for example, they suffer from cardiovascular disease in Low blood pressure levels.
If these conditions mostly affect men, there will be more treatments available
But there is still a job to do. While many financiers now insist that research includes two sexes, the conditions that often affect women – such as migraines, uterine lining, and reproductive disorder (see “Surprising visions in PMDD causes are better treatments”) – communication Attractive financing is much lower In proportion to the burden of the population. The hormones and their actions make research more complicated should be the reason for investing more, not less.
If these conditions mostly affect men, there will be no doubt more treatments available. The stories of people who live with PMDD should be read as a blatant reminder at the cost of this inequality.
Topics: