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The ultimate comeback: the science of resurrection

Thank you, O God, for this amazing
Today: The souls of green trees jump
A real blue dream from the sky. And for all
It is an endless natural thing that is yes

American poet Cameting He wrote this, apparently on Easter on Sunday. And it continues: “(I who died alive again today, and this is the birthday of the sun; this is the birthday of life, love and wings.”

Linking a new birth with courses in nature is not just a Christian or even religious thing. In moderate climates, especially the life that appears to die in autumn every year it is revived in the spring. Even when the trees do not drop their leaves and the ground does not sleep under a blanket of ice, accurate changes may indicate slowing, retreating, and feeling suspended animation. And now, in the spring, with the start of the flow, the buds begin to form and the buds begin to spread, life is revived. Animals It comes out of the hibernationLike Sleeping Beauty, she woke up from her death -like sleep for 100 years.

But some animals, a few other organisms, take the measurement a step forward: it seems to be dead, apparently, they return to life.

Take a strange look tardigrade-like a cross between a tank and a teddy bear, and is famous for the inability to influence. Under the harsh conditions, Tardigrades may participate in encryption, a process that may become completely dried and traded in a small ball called “TUN”.

“Tardigrades form tubes by contracting their muscles and expelling water simultaneously, leading to a decrease in total size,” Derek Kulling, head of the Chemistry Department at Marshall University and head of the Kolling Laboratory, which focuses on Tardigrade, told Salon.

Then it is said that tardigrade in “Tun State”. It can remain like this for weeks before revival under more convenient circumstances. It has been proven that some species were working well (i.e. a large percentage of individuals who studied alive) when moisturizing More than seven months after encryption. and Two weeks after exposure to low orbit space While in their dried state, Tardigrades “unambiguously” returned to life (although two years after this treatment, which also involves exposure to cosmic radiation, there was no resurrection). In another study, one type of tardigrade has been revived After 20 years as a small dried ball.

“One of the criteria related to something to be considered alive is metabolism,” Kolling pointed out, “and even in the maximum case of a full metabolism stop stop, Tardigrades still has a network of enzymes that can decrease and activate – in this case, I will consider it alive.

Continue breathing …

… Firstly. Naked mole mice are unique mammals in many respects. They have a complex social life, for example. They are Eusocial, an animal -applied description – including bees, wasps, some other insects, some gentle shrimp and strange mammals – that have a complex social organization that includes The overlap of generations, cooperative education of the young and non -producing class. The blood temperature fluctuates with the surrounding temperature, which is a rare feature among the mammals they share with laziness.

Perhaps it is more surprising, they can – apparently – die for a short time when the surrounding oxygen levels are very low, or completely absent. This is true: In the tunnels in which naked mole mice spend their life, humidity levels can approach 100 % and accumulate carbon dioxide thanks to dozens of young players wrinkles in the very low oxygen environment already. So bare naked mice are chronicly deprived of oxygen, but in the laboratory the researchers emphasized that they can survive for a short period without any oxygen at all.

“In nature, naked mole mice are not exposed to oxygen oxygen (0 % oxygen) [conditions]But when they were exposed to it in the laboratory, they survived for 18 minutes and it is very impressive! In their tunnels, they are discussed whether they suffer naturally from the conditions of hypoxia (low oxygen), but when they are exposed to these conditions in the laboratory, they are subject to depression of metabolic rate, “Hanan Hadiga Moussa said for treatment.

Reducing the rate of metabolism and slowing heart is bare nude mice with most of the revival animals. But they also have a unique adaptation: switching the power source from glucose to fructose.

“This is a strange adaptation, but it allows them to perform anaerobic decomposition,” said Hadj-Moussa. This means that during these low oxygen periods, they can generate energy from fructose without the need to use rare oxygen to do so, as it requires energy generation in the usual way of glucose. “Activating nervous protection mechanisms and heart ability to reduce damage.”

After that, when it is time for the resurrection, Hadj-Moussa explained, “They are” repeating “by contrary to what they did to depressed their metabolism, and they return to glucose metabolism, all with high antioxidant levels.”

Stay cold

As with the world that freezes in the winter, then returns to life, the resurrection often involves the cold. Among these wooden frogs, Canadian amphibians freeze for eight months of the year.

“One of the main preventive adjustments of frogs is their ability to dehydrate simultaneously from its cells with pumping full of glucose to prevent and reduce the formation of ice crystals inside the cells, which is much more dangerous than freezing their body water in its areas outside the cell”, “Mousss, who studied from wood, tolerance of the swallow cavity. She explained that each molecule of glucose surrounds itself with water molecules. Water glucose from the formation of ice crystals that transports cells, which reduces the temperature required to freeze them. Since the cells have also been dried, there is less water inside.

The first ice crystal formula forms on the skin of the frog wood leads to a series of chemical signals that “prepare the frog for tolerance for freezing and depression in the metabolic rate. This waterfall leads the liver to the production of huge amounts of glucose, [adjusts] Hadj-Youssa said that the heart rate is to ensure that the heart can pump blood rich in glucose to all the cells you need, and this begins to slow the organs and operate protection mechanisms.

After a few years of working on the frog wood in Ottawa, Rasha Al Uttar, who is now working Harvard Medical Shawto The Massachusetts General Hospital Center for Engineering in Medicine and Surgery, as it is inspired by nature to develop refrigeration techniques for typical typical animals such as zebra, or to preserve organs such as human hearts.

The mechanisms that animals use to hibes or slow the metabolism process are similar to the unsuccessful seasonal conditions that are used by biological creatures, which are more extreme on this topic. As Attar and MR.SC. Supervisor, Ken Story, Books on paper 2020“While there are many forms of depression in the metabolism rate, the basic theory remains the same … cellular processes and non -critical metabolism are assigned to a large extent, and the limited amount of energy reserves available to enhance pro -corruption” such as preserved frog.

A little

Permanent harsh conditions are one thing. Then there is prosperous in it. When you can do this, you are called Extremophile. Extremophiles forms another set of revival. Many bacteria or other microbes. Luis Andres Yarzali, the microbiologist in Universidad Católica de Cuenca In Ecuador, the sudden results of Russian scientists study the ice cores extracted from the virgin ice rivers in the Antarctica in the eighties.

“When they started looking at them with a microscope, they discovered a lot of microbes. Many had died, of course, but others were alive and reactivated very quickly. “In fact, this is what we are [as scientists] Do to maintain our bacterial strains, and we stent them, in our extremist freezers in minus 80 degrees. So it is not surprising that microorganisms are alive, but also viable, which means that they can start dividing again. “

Yarzábal explained that living organisms that can survive in this suspended situation, or innovation, not only include extremist bacteria, but also include viruses, fungi, protozoa and microscopic animals called nematode. The dissolved salts in the water ensure that there is a very small amount of water in a liquid state in the facade between ice crystals. Microorganisms can be displaced to this small space, where they avoid infection from ice crystals and survival although the metabolism rate remains almost unlikely, so they practically do not spend any energy on life functions, instead in spending their time until conditions improve.

For EE Cummings, such as former American transcendent poets such as Ralph Walou Emerson and Henry David Thoro, attention was everything. And when the creativity of nature performs magical work enough to describe it as a resurrection, there is a lot of wonder in joining it. This time of the year invites us all, believers and atheists alike, to get out of our animation or cheeks, such as the Kamings at the end of that poem:

Now my ears are awake and
Now my eyes are opened

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