UK scientists develop DNA sequencing system to fight superbugs | Antibiotics

Scientists have developed a rapid DNA sequence system to stop the rise of superior errors by identifying bacterial infections faster and more accurate.
Currently, hospital laboratories can take up to seven days to determine bacterial infections, while the final diagnosis for some infections may take eight weeks.
Meanwhile, doctors may have to give patients with broad -spectrum antibiotics, which bear the risk of side effects and complications, may fail in the disease, and can lead to antibiotic resistance and prevailing mistakes spread through the wings.
Now the scholars have developed a solution. In the UK first, the Agency for Medicines and Healthcare Products (MHRA) and Barts health London NHS TRST designed the DNA to diagnose bacterial infections faster and more accurate.
The DNA sequence includes reading the genetic code of bacteria. Experts say it is closer to reading the instructions guide that tells bacteria how to work.
It enables scientists to determine the specified type of bacteria and any antibiotics that may be resistant to it, which helps doctors to give the patient the most effective treatment, instead of widespread antibiotics.
The pioneering system, which succeeded in 2000 NHS Patients, doctors already help provide better targeted treatments earlier. This means much faster recovery, less complications such as blood rot, and a lower degree of danger of others who pick up infection and the emerging gestures of the wings.
The new method can reliably discover any bacteria that cause an infection that will work the best antibiotics to treat. The approach provides results within 48 hours, much faster than traditional methods.
Experts say this penetration paves the way for the fast DNA sequence to become a routine part of NHS hospital diagnosis, which brings a faster and more accurate test for patients at the national level.
Dr. Kraisy Sergaki, head of the microbium at MHRA, said that the fast DNA sequence was “decisive in the fight against news.”
“The pilot has proven that this new technology has already caused a real difference in patients’ life. When someone comes to the hospital with a serious infection, every important hour.
“Instead of waiting days or even weeks to determine exactly the cause of their enemies, hospitals can now get answers within 48 hours. This means that doctors can start the correct treatment sooner, which helps patients to recover faster and return to their families.”
Ian Butler, the main clinical world of medical microbiology in Barts, said that traditional diagnoses depended on the growing bacteria in the laboratory of patient samples.
This may take a week or more and “lack allergies”, especially in patients who are already suffering from widely antibiotics for serious infections, such as poisoning or meningitis.
“Since the use of broad -spectrum antibiotics can reduce the patient’s bacterial return, these cultures often result in negative results, which means that bacteria fail to grow in the laboratory.
“This makes it difficult to obtain a final diagnosis, leaving patients with long long antibiotic therapy, which not only delays effective treatment, but also increases the risk of antibiotics resistance.”
Bater said the fast DNA sequence, in contrast, can discover the infection specified in clinical samples even when bacteria are damaged or their levels have decreased dramatically due to the previous antibiotic treatment.
“By identifying bacteria quickly and precisely, especially in patients previously treated with antibiotics, we can manage the correct targeted antibiotics sooner. This ensures a much faster recovery while reducing the risk of side effects and complications associated with broad -spectrum antibiotics.
“Not all antibiotics are effective against all the specific bacteria and bacteria are more likely to some antibiotics than others. If the wrong antibiotics are used, treatment may fail, which leads to long illness and greater risk to the patient. This makes it necessary to determine the exact cause of infection to provide the safest and most effective treatment.”
World Health Organization described Superbugs as “one of the best threats of public health and global development.”
Last month, a national auditing report warned that they had already contributed to more than 35,000 deaths annually in the United Kingdom and that the government “is still far from achieving its goal of containing and controlling it.
Pateler said that the use of wide -spectrum antibiotics with a fast DNA sequence can help to convert tide in the war on errors.
He said: “The prolonged use of broad-spectrum antibiotics not only affects the individual patient-but rather it can enhance bacterial mutations, which leads to antibiotics resistance and the emergence of super errors.”
“These highly fatal errors can cause deadly infections, such as the difficult blood rot, and as soon as it is established, it can spread inside hospitals. This puts other patients – especially those who are already seriously suffering – at greater risk.
“By quickly identifying infections and providing accurate treatment, this new approach not only improves the results of the patient, but also helps in preventing superpowers that resist antibiotics in hospitals, and protect future patients and the broader audience.”