Peanut is one of the most common foods that people suffer from
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Adults with peanut allergy reduce the risk of reactions by eating a little peanut protein every day as part of the experiment. This approach has already been approved in the United States for children with this condition.
Sudanese bean sensitivity occurs at The immune system Proteins error in legumes are determined as a threat. It responds to the production of more IGE antibodies, which are a vital part of the immune response, but they are wrong to allergic reactions. As a result, infections increase, causing symptoms such as swelling, itching and vomiting. In extreme cases, it can lead to an allergy shock, a life -threatening reaction that can affect a person’s breathing or heart rate.
Until recently, the only solution was to avoid peanuts, but intervention called oral immunotherapy for children with allergies in the United States was approved in 2020. This involves training the immune system to withstand allergies by exposing it to increased doses of peanut proteins gradually.
However, it was not clear whether the approach was also working in adults. He says: “Most of the life of an allergic person in peanuts is spent as an adult, but we had no treatment to reduce his primary interaction on peanuts,” he says. Stephen even At King’s College London. “There are some causes of doubt that adults will be more difficult than children’s sensitivity because your immune system is easier when you are younger.”
To fill this knowledge gap, he enlisted and his colleagues are 21 adults with peanut allergy. At the beginning of the study, the participants were only able to eat up to the eighth peanuts, on average, before they had an allergic reaction.
The team had every participant who eaten the equivalent protein in one of 40 peanuts every day for two weeks. This dose has been increased slightly every two weeks for several months, so that they can take the protein safely and consistently for four large peanuts every day for a month.
Three participants came out of the study due to allergic reactions, while three others left for reasons that have nothing to do with treatment. “This leakage number is acceptable to this type of treatment,” he says. Cezmi Akdis At the Swiss Institute of Allergy and Asthma Research.
The remaining 15 participants participated in the allergy test, where they took increasing doses of peanut protein under the supervision of researchers. Each of them, except for one, was able to eat the equivalent of five peanuts without an allergic reaction.
In another part of the experiment, the team analyzed the blood samples collected from the participants before and after receiving oral immunotherapy. This is revealed that the intervention caused them to get higher levels than IGG AntibodiesWhich contradicts the effects of IIG antibodies.
“It is very promising,” says Adehis. “This approach may mean that adults with peanut allergies can relieve anxiety of peanut eating.”
But this was a relatively early stage experience, and greater procedures are needed to verify the results and determine the period of protection, he says. “I expect you will need to take doses daily or regular peanuts in the long run to keep tolerance with allergens,” Akdis says. “People have birth control pills every day, so I think people affected by peanut allergies may be good in this type of method.”
You should never try to treat allergies without medical supervision.
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